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The most common side effects reported in the tirzepatide groups were diarrhea and nausea.In patients with type 2 diabetes who had inadequate control of blood sugar levels despite treatment with insulin glargine, adding subcutaneous tirzepatide to titrated insulin glargine led to significant improvements in glycemic control after 40 weeks, along with reductions in body weight

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While these effects can be beneficial to those dealing with high BMIs or obesity, the endurance athlete, who requires large energy sources to perform and compete, will typically find that these effects would decrease performance to a degree, he says